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Lymphoma is a type of cancer that is common in cats and can be seen in almost every organ. Cutaneous lymphoma is a rare form that occurs in the skin. Less than 2% of lymphoma cases in cats occur in the skin.
Feline cutaneous lymphoma can present various clinical signs, including itching, alopecia (hair loss), scaly skin, skin redness, loss of skin color, ulcers, nodules, pustules, and plaques.
As cutaneous lymphoma progresses, the skin becomes thickened, reddened, ulcerated, and may ooze fluid. While any skin area may be affected, the most common locations to find cutaneous lymphoma lesions include the junction between mucus membranes and the skin. Examples include the lip margins, eyelids, around the nose, anus/rectum, vulva, and the prepuce of the penis.
Cutaneous lymphoma is diagnosed by skin biopsy, which is the removal of affected tissue to be examined by a veterinary pathologist in a laboratory. It may spread to lymph nodes in the area of the skin lesions, which is the disease’s pathway to the rest of the body. Once the lymph nodes are involved, systemic spread to the organs can occur.
Unfortunately, feline cutaneous lymphoma is considered incurable. Surgical removal can be attempted for solitary lesions, although the tumor often returns to the area or has already spread elsewhere in the body. Palliative chemotherapy or radiation therapy may slow progression and contribute to survival time. Supportive care using antibiotics is important for treating concurrent skin infections.
This condition comes with a grave prognosis. On average, cats diagnosed with cutaneous lymphoma and given treatment will live only 6–12 months. This disease is complex and discouraging for both cats and their owners.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Apr 17, 2025.
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